2023年度は4名の推薦（応募）があった。
［受賞理由］
ストレス感受性とレジリエンスに関する遺伝子環境相互作用動物モデルを用いて、繰り返しストレスによって誘発される行動変化の根底にある分子・細胞レベルのメカニズムを明らかにした。
［受賞対象論文］
GPCR-mediated calcium and cAMP signaling determines psychosocial stress susceptibility and resiliency
Science Advances vol. 9,14 (2023)
2022年度は4名の推薦（応募）があった。
［受賞理由］
統合失調症のシナプス分子自己抗体の探索から、これまで知られていなかった抗NCMA1抗体を見出し、統合失調症サブタイプの病態機序とバイオマーカーとして提起し、動物実験にもとづいて治療への示唆を明らかにした。
［受賞対象論文］
・Autoantibodies against NCAM1 from patients with schizophrenia cause schizophrenia-related behavior and changes in synapses in mice.
Cell Reports Medicine. 2022 3(4):100597.
2021年度は6名の推薦（応募）があった。
［受賞理由］
幅広い精神神経疾患と電気けいれん療法を結びつけ、臨床的な着眼点からの研究を行い、有用なデータを発表している。
［受賞対象論文］
Neural Substrates of Psychotic Depression: Findings from the Global ECT-MRI Research Collaboration.
Schizophrenia Bull 2021 (Online ahead of print)
Lower regional gray matter volume in the absence of higher cortical amyloid burden in late-life depression.
Sci Rep 2021; 1 1 (l): 15981.
Biophysical mechanisms of electroconvulsive therapy-induced volume expansion in the medial temporal lobe: A longitudinal in vivo human imaging study.
Brain Stimul 2021; 14: 1038_1047.
Electroconvulsive Therapy for Patients With Depression Who Lack Capacity for Consent: Doing Good and Doing No Harm.
J ECT 2021; 37:171-175.
Association of electroconvulsive therapy-induced structural plasticity with clinical remission.
Prog Neuropsychopharmacol Biol Psychiatry 2021; 110: 110286
Electroconvulsive Therapy for Parkinson's Disease: A Systematic Review and Meta-analysis. Mov Disord 2021; 36(1): 50_58.
［受賞理由］
双極性障害の遺伝子解析において科学的先駆性、独自性に富む優れた研究成果を国際的に評価の高い学術誌に掲載している。
［受賞対象論文］
Systematic analysis of exonic germline and postzygotic de novo mutations in bipolar disorder
Nature Communications volume 12:3750 (2021)
2020年度は5名の推薦（応募）があった。
[受賞理由]
さまざまな疾患や病態を対象に、臨床の発展に結びつくことが期待できる先進的な内容の論文を優れた雑誌に数多く発表しており、今後のさらなる発展が期待できる研究者である。
[受賞対象論文]
White matter microstructural alterations across four major psychiatric disorders: mega-analysis study in 2937 individuals.
Molecular Psychiatry. 2020 Apr;25(4):883-895.
Reduced Auditory Mismatch Negativity Reflects Impaired Deviance Detection in Schizophrenia.
Schizophrenia Bulletin. 2020 Jul 8;46(4):937-946.
Association between duration of breastfeeding based on maternal reports and dorsal and ventral striatum and medial orbital gyrus volumes in early adolescence.
Neuroimage. 2020 Oct 15;220:117083.
Resting-state EEG beta band power predicts quality of life outcomes in patients with depressive disorders: A longitudinal investigation.
Journal of Affective Disorders. 2020 Mar 15;265:416-422
Association between the superior longitudinal fasciculus and perceptual organization and working memory: A diffusion tensor imaging study.
Neuroscience Letters. in press. 2020.
2019年度は7名の推薦（応募）があった。
[受賞理由]
てんかんおよびてんかんに関連する精神症状について、多面的な研究を継続してきている研究者であり、今年度の受賞対象論文はAIなど先進的な研究手法を用いたもので、インパクトファクターの高い雑誌に掲載された論文であった。
[受賞対象論文]
Neuroimaging-based brain-age prediction in diverse forms of epilepsy: a signature of psychosis and beyond.
Molecular Psychiatry. 2019 Jun 3. [Epub ahead of print]
2018年度は6名の推薦（応募）があった。
久島 周 会員
[受賞理由]
日本人を対象に自閉症と統合失調症のコピー数多型copy-number variation (CNV)を検討し、その臨床的な意義を明らかにするとともに、両疾患に共通する所見があることにもとづいて病因における意義について洞察を深めた。
[受賞対象論文]
Comparative analyses of copy-number variation in autism spectrum disorder and schizophrenia reveal etiological overlap and biological insights.
Cell Rep. 2018 Sep 11;24(11):2838-2856
[受賞理由]
ノルエピネフリン・トランスポーターのPET研究に取り組み、世界初の所見などの先進的な成果を複数の優れた論文として発表している。
[受賞対象論文]
Norepinephrine Transporter in Major Depressive Disorder: A PET Study
Am J Psychiatry. 2017 Jan 1;174(1):36-41.
PET Quantification of the Norepinephrine Transporter in Human Brain with (S,S)-18F-FMeNER-D2
J Nucl Med. 2017 Jul;58(7):1140-1145
Occupancy of Norepinephrine Transporter by Duloxetine in Human Brains Measured by Positron Emission Tomography with (S,S)-[18F]FMeNER-D2
Int J Neuropsychopharmacol. 2017 Dec 1;20(12):957-962
[受賞対象論文]
Pharmacogenomic Study of Clozapine-Induced Agranulocytosis / Granulocytopenia in a Japanese Population.
Biological Psychiatry. 2016 Oct 15;80(8):636-42.
Transethnic Replication Study to Assess the Association Between Clozapine-Induced Agranulocytosis/Granulocytopenia and Genes at 12p12.2 in a Japanese Population.
Biol Psychiatry. 2016 Dec 16. [Epub ahead of print]
[受賞対象論文]
Differential patterns of blood oxygenation in the prefrontal cortex between patients with methamphetamine-induced psychosis and schizophrenia
Scientific Reports. 2015 Jul 16;5:12107.
[受賞対象論文]
Oxytocin improves behavioural and neural deficits in inferring others’ social emotions in autism.
Brain. 2014 Nov;137(Pt 11):3073-86. Epub 2014 Aug 22.
Oxytocin’s neurochemical effects in the medial prefrontal cortex underlie recovery of task-specific brain activity in autism: a randomized controlled trial.
Molecular Psychiatry. 2015 Apr;20(4):447-53. Epub 2014 Jul 29.
[受賞対象論文]
DNA methylation signatures of peripheral leukocytes in schizophrenia.
Neuromolecular Med. 2013 Mar;15(1):95-101
Plasma total homocysteine is associated with DNA methylation in patients with schizophrenia
Epigenetics. 2013 Jun;8(6):584-90
[受賞対象論文]
Effects of risperidone and olanzapine dose reduction on cognitive function in stable patients with schizophrenia: an open-label, randomized, controlled, pilot study.
Schizophr Bull. 2013 Sep;39(5):993-8
Estimated dopamine D2 receptor occupancy from plasma concentrations of atypical antipsychotics and subjective experience/drug attitude in schizophrenia: An analysis of the CATIE data
Schizophr Res. 2013 Nov;150(2-3):373-9
Impact of once- versus twice-daily perphenazine dosing on clinical outcomes: an analysis of the CATIE data.
J Clin Psychiatry. 2014 Feb 4. [Epub ahead of print]
[受賞対象論文]
Gamma Band Neural Synchronization Deficits for Auditory Steady State Responses in Bipolar Disorder Patients.
PLoS ONE Volume7 Issue 7 e39955, July 2012
第109回日本精神神経学会総会 精神医学奨励賞受賞講演 （2.02MB）
［受賞対象論文］
Glucose tolerance status and risk of dementia in the community: the Hisayama Study. Neurology. 77(12): 1126-1134, 2011.
Apolipoprotein genotype for prediction of Alzheimer's disease in older Japanese: the Hisayama Study.
J Am Geriatr Soc. 59(6): 1074-79, 2011.
第108回日本精神神経学会総会 精神医学奨励賞受賞講演 （341KB）
[受賞対象論文]
Identification of novel candidate genes for treatment response to risperidone and susceptibility for schizophrenia.
Biol Psychiatry 67(3)p263-9,2010
Copy number variation in schizophrenia in the Japanese population.
Biol Psychiatry 67(3)p283-6,2010
Genome-wide association study of schizophrenia in a Japanese population.
Biol Psychiatry In press 2010
第107回日本精神神経学会総会 精神医学奨励賞受賞講演 （471KB）
[受賞対象論文]
A self-reported instrument for prodromal symptoms of psychosis:Testing the clinical validity of the PRIME Screen-Revised (PS-R) in a Japanese population.
Schizophrenia Research,Dec 106 (2-3),356-362,2008
The effects of aripiprazole on insight and subjective experience in individuals with an at-risk mental state.
The Journal of Clinical Psychopharmacology, 29(5);421-425,2009
第106回日本精神神経学会総会 精神医学奨励賞受賞講演 （313KB）
[受賞対象論文]
Abnormal neural oscillatory activity to speech sounds in schizophrenia: a magnetoencephalography study.
The Journal of Neuroscience. 2008 May 7;28(19):4897-903.
第105回日本精神神経学会総会 精神医学奨励賞受賞講演 （630KB）
[受賞対象論文]
Risperidone significantly inhibits interferon-gamma-induced microglial activation in vitro.
Schizophrenia Research. 2007 May;92(1-3):108-15.
第104回日本精神神経学会総会 精神医学奨励賞受賞講演 （490KB）
[受賞対象論文]
Morphologic alterations of the parcellated superior temporalgyrusin schizophrenia spectrum.
Schizophr Res 2006;83 : 131-43.
Temporal lobe gray matter in schizophrenia spectrum: a volumetric MRI study of the fusiform gyrus, parahippocampal gyrus, and middle and inferior temporal gyri.
Schizophr Res 2006;87 : 116-26.
Volume reduction of the left planum temporale gray matter associated with long duration of untreated psychosis in schizophrenia : a preli minary report.
Psychiatry Res 2007;154 : 209-19.
[受賞対象論文]
Hippocampal Complexin Proteins and Cognitive Dysfunction in Schizophrenia.
Arch Gen Psychiatry: Vol62,263-272,2005
Vulnerability of synaptic plasticity in the complexin Ⅱ knockout mouse to maternal deprivatin stress.
Brain Res. 2005 Sep 14;1056(1):59-67.
第102回日本精神神経学会総会 精神医学奨励賞受賞講演 （470KB）
該当者なし
[受賞対象論文]
Inhibitory Effect of Hippocampal 5-HT1A Receptors on Human Explicit Memory.
Am .J Psychiatry 2003; 160: 334-340
第100回日本精神神経学会総会 精神医学奨励賞受賞講演 （694KB）
[受賞対象論文]
Lithium protection against glutamate excitotoxicity in rat cerebral cortical neurons: involvement of NMDA receptor inhibition possibly by decreasing NR2B tyrosine phosphorylation.
J.Neurochem.,80:589-597,2002.
Lithium Induces Brain derived Neurotrophic Factor and Activates TrkB in Rodent Cortical Neurons: An Essential Step for Neuroprotection against Glutamate Excitotoxicity,
Neuropharmacology. 2002 Dec;43(7):1173-9.
Lithium Stimulates Progenitor Prolife ration in Cultured Brain Neurons
Neuroscience. 2003;117(1):55-61
第99回日本精神神経学会総会 精神医学奨励賞受賞講演 （157KB）
該当者なし
[受賞対象論文]
Neural correlates of memory organization deficits in schizophrenia.A single photon emission computed tomography study with 99m Tc-ethyl-cysteinate dimer during a verbal learning task.
Schizophr Res.2000 May 5;42（3):209-22.
該当者なし
[受賞対象論文]
Lower Left Temporal Lobe MRI Volumes in Patients With First ― Episode Schizophrenia Compared With Psychotic Patients With First ― Episode Affective Disorder and Normal Subjects
Am J Psychiatry. 1998 Oct;155(10):1384-91.
